Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50109958((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)Copy SMILESCopy InChI

Affinity DataIC50:  1nMAssay Description:Inhibitory activity against very late antigen-4 (VLA-4) using VCAM-Ig ligand.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50109958((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)Copy SMILESCopy InChI

Affinity DataIC50:  3.55E+3nMAssay Description:Inhibition of MadCAM-Ig binding to alpha-4 beta-7 integrinMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI