Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 37 hits in this display
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 0.900nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 68nMAssay Description:Inhibition of PARP-3 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 185nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 2.40E+3nMAssay Description:Inhibition of PARP-12 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 2.70E+3nMAssay Description:Inhibition of PARP-11 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 8.40E+3nMAssay Description:Inhibition of PARP-8 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 1.10E+4nMAssay Description:Inhibition of PARP-10 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 1.10E+4nMAssay Description:Inhibition of PARP-7 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: >1.00E+5nMAssay Description:Inhibition of PARP-6 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 1.85E+5nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
IC50: 1.85E+5nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
BDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)