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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
18
hits in this display
Target
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: 1nM
Assay Description:
Inhibition of human ATX assessed as reduction in LPA formation using FS-3 as substrate preincubated for 30 mins followed by substrate addition and me...
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Target
Lysophosphatidic acid receptor 1
(Rattus norvegicus)
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: 47nM
Assay Description:
Inhibition of LPA in rat plasma after 18 hrs by LC-MS/MS analysis
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: 53nM
Assay Description:
Inhibition of LPA in human plasma after 18 hrs by LC-MS/MS analysis
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes incubated for 15 mins in presence of NADPH by LC-MS/MS analysis
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes incubated for 15 mins in presence of NADPH by LC-MS/MS analysis
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Target
Sphingosine 1-phosphate receptor 1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of S1P1 (unknown origin)
More data for this Ligand-Target Pair
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Target
Sphingosine 1-phosphate receptor 2
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of S1P2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Sphingosine 1-phosphate receptor 3
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of S1P3 (unknown origin)
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Target
Sphingosine 1-phosphate receptor 4
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of S1P4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Sphingosine 1-phosphate receptor 5
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of S1P5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Lysophosphatidic acid receptor 1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of LPA1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Lysophosphatidic acid receptor 2
(Homo sapiens)
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of LPA2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Lysophosphatidic acid receptor 3
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of LPA3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Lysophosphatidic acid receptor 5
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of LPA5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes incubated for 30 mins in presence of NADPH by LC-MS/MS analysis
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP1A2 in human liver microsomes incubated for 15 mins in presence of NADPH by LC-MS/MS analysis
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human ERG by automated patch-clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50572947
(CHEMBL4871014)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CYP3A4 in human liver microsomes incubated for 15 mins in presence of NADPH by LC-MS/MS analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Ligand Info
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PC cid
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In Depth
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Article
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