Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

LigandPNGBDBM50132634((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-pyridin-3...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant tumor necrosis factor-alpha converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132634((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-pyridin-3...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132634((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-pyridin-3...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Tumor necrosis factor-alpha (TNF-alpha) release in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50132634((2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-pyridin-3...)
Affinity DataIC50:  3.40E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed