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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50590214
(CHEMBL5208974)
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Affinity Data
IC50: 9nM
Assay Description:
Inhibition of recombinant human GST20 tagged truncated LRRK2 G2019S mutant assessed as substrate phosphorylation preincubated for 15 mins followed by...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50590214
(CHEMBL5208974)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Inhibition of human LRRK2 G2019S mutant expressed in human SH-SY5Y cells assessed as inhibition of tetracycline induced LRRK2 phosphorylation at Ser9...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM50590214
(CHEMBL5208974)
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Copy InChI
Affinity Data
IC50: 124nM
Assay Description:
Inhibition of CLK2 (unknown origin) assessed as substrate phosphorylation using coumarin and fluorescein-labeled peptide as substrate incubated for 1...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI