Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetFatty acid synthase(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  850nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  2.23E+3nMAssay Description:Inhibition of FAS in human ZR-75-1 cells by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  2.50E+3nMAssay Description:The compound was tested for its affinity against HIV-1 protease in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human FAS assessed as synthesis of long chain fatty acids from malonyl CoA after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Yeungnam University

LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  1.30E+4nMpH: 7.0 T: 2°CAssay Description:To each microtube (final volume: 100 μL), FAS was added (20-30 μg protein) in a buffer containing 100 mM potassium phosphate (pH 7.0), 2.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of F13-A in human plasma assessed as inhibition of fibrin clot formation by biotin incorporation assay in presence of 1 mM reduced GSHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of FASN in human A375 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009248((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)
Affinity DataIC50:  2.50E+6nMAssay Description:The compound was tested for its affinity against HIV-2 protease (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed