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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Acerta Pharma
US Patent
Ligand
BDBM515333
(US11110088, Compound Table 1.7)
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Affinity Data
IC50: 1.60nM
Assay Description:
BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Tyrosine-protein kinase Tec
(Homo sapiens (Human))
Acerta Pharma
US Patent
Ligand
BDBM515333
(US11110088, Compound Table 1.7)
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Affinity Data
IC50: 2nM
Assay Description:
TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Tyrosine-protein kinase TXK
(Homo sapiens (Human))
Acerta Pharma
US Patent
Ligand
BDBM515333
(US11110088, Compound Table 1.7)
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Affinity Data
IC50: 2.10nM
Assay Description:
TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
Acerta Pharma
US Patent
Ligand
BDBM515333
(US11110088, Compound Table 1.7)
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Affinity Data
IC50: 2.90nM
Assay Description:
BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Acerta Pharma
US Patent
Ligand
BDBM515333
(US11110088, Compound Table 1.7)
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Affinity Data
IC50: 287nM
Assay Description:
ITK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.ITK enzyme (M...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Acerta Pharma
US Patent
Ligand
BDBM515333
(US11110088, Compound Table 1.7)
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Affinity Data
IC50: 549nM
Assay Description:
EGFR enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.EGFR enzyme ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI