Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50: <1nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50:  19nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50:  257nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187786(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed