Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
Assay Description:
Inhibition of TACE by FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.60nM
Assay Description:
Inhibition of TACE in human whole blood assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 46nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 46nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 191nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 191nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 553nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 583nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.01E+3nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Wyeth Research
Curated by
ChEMBL
Ligand
BDBM50187795
(4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.01E+3nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI