Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126601(4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126601(4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126601(4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126601(4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  244nMAssay Description:Inhibitory activity against matrix metalloproteinase 9 (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126601(4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase 1 (MMP-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed