Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50162732(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(4-dimethyla...)Copy SMILESCopy InChI

Affinity DataIC50:  75nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50162732(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(4-dimethyla...)Copy SMILESCopy InChI

Affinity DataIC50:  395nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI