Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50:  3.27E+3nMAssay Description:Inhibition of MMP2 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50:  4.44E+3nMAssay Description:Inhibition of MMP13 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50:  6.98E+3nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50:  6.98E+3nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of MMP14 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50279287(3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynylox...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of MMP1 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed