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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50:  76.5nMAssay Description:Inhibitory concentration against human ECE-1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against NeprilysinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Institute Of Pathology

Curated by ChEMBL
LigandPNGBDBM50159366((2S,4R)-4-Acetylsulfanyl-2-(2,4,5-trifluoro-benzyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against human angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed