Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50467645(CHEMBL4288038)Copy SMILESCopy InChI

Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged SYK expressed in baculovirus expression system using Biotin-AAAEEIYGEI as substrate after 60 m...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Glaxosmithkline R&D

Curated by ChEMBL

LigandBDBM50467645(CHEMBL4288038)Copy SMILESCopy InChI

Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI