Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50292983(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)Copy SMILESCopy InChI

Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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TargetMotilin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50292983(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)Copy SMILESCopy InChI

Affinity DataEC50:  31.6nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI