Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  2.66E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured after 18 to 24 hrs by HRP based luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  1.94E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells in presence of CFTR corrector C1 by CRE- horseradish peroxidas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  2.61E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells by CRE- horseradish peroxidase-coupled high throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50504992(CHEMBL4521957)
Affinity DataEC50:  1.97E+3nMAssay Description:Corrector activity at CFTR F508del mutant (unknown origin) expressed in CFBE41o- cells measured at 18 to 24 hrs in presence of 3-((2R,4S)-4-(1-(2,2-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed