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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  8nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(CHEMBL379665 | rac-N-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  24nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(CHEMBL379665 | rac-N-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  29nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(CHEMBL438962 | N-(((1R,3S)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  72nMAssay Description:Inhibition of [125]I-motilin binding to rabbit motilin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186108(CHEMBL209301 | N-(((1S,3R)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  338nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(CHEMBL438962 | N-(((1R,3S)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  638nMAssay Description:Activity at rabbit duodenum motilin receptor by tissue contractility assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186111(CHEMBL379665 | rac-N-((3-(N-benzylpivalamido)cyclo...)
Affinity DataIC50:  990nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMotilin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50186112(CHEMBL438962 | N-(((1R,3S)-3-(N-benzylpivalamido)c...)
Affinity DataIC50:  2.48E+3nMAssay Description:Activity at human motilin receptor transfected in HEK293 cells assessed as inhibition of motilin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed