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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Voltage-dependent T-type calcium channel subunit alpha-1H
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: 600nM
Assay Description:
Inhibition of human T-type calcium channel Cav3.2 expressed in T-Rex293 cells by whole cell patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
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Target
Voltage-dependent T-type calcium channel subunit alpha-1H
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of T-type calcium channel Cav3.2 (unknown origin) by IONWORKS assay
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Article
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP2C19
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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CHEMBL
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PC sid
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Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 2C8
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human recombinant CYP2C8
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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CHEMBL
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In Depth
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Article
PubMed
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: 1.30E+4nM
Assay Description:
Inhibition of human recombinant CYP2D6-mediated 7-methoxy-4(aminomethyl)-coumarine degradation
More data for this Ligand-Target Pair
Target Info
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Target
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >3.16E+4nM
Assay Description:
Inhibition of calcium channel Cav1.2 (unknown origin) expressed in CHO cells by IONWORKS patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >3.30E+4nM
Assay Description:
Inhibition of human ERG expressed in CHO cells by IONWORKS assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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CHEMBL
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Target
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >3.30E+4nM
Assay Description:
Inhibition of human Nav1.5 channel expressed in CHO cells by IONWORKS patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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Target
Potassium voltage-gated channel subfamily D member 3
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >3.30E+4nM
Assay Description:
Inhibition of human Kv4.3 channel expressed in CHO cells by IONWORKS patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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CHEMBL
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In Depth
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Article
PubMed
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Target
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50428594
(CHEMBL2337981)
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Affinity Data
IC50: >3.30E+4nM
Assay Description:
Inhibition of human HCN4 channel expressed in CHO cells by IONWORKS patch clamp assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI