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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human))
University Of Pennsylvania
Curated by
ChEMBL
Ligand
BDBM50288523
(CHEMBL4177509)
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Affinity Data
IC50: 453nM
Assay Description:
Binding affinity to PARP1 in human OVCAR8 cells assessed as reduction in [125I]-KX1 binding by gamma counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human))
University Of Pennsylvania
Curated by
ChEMBL
Ligand
BDBM50288523
(CHEMBL4177509)
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Copy InChI
Affinity Data
IC50: 2.80E+3nM
Assay Description:
Inhibition of human N-terminal GST-tagged TNKS2 (667 to 1166 residues) expressed in baculovirus infected sf9 cells using histone as substrate after 1...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human))
University Of Pennsylvania
Curated by
ChEMBL
Ligand
BDBM50288523
(CHEMBL4177509)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.70E+3nM
Assay Description:
Inhibition of human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells using histone as substrate after ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI