Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

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TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent

LigandBDBM281050(US10022352, Compound 311)Copy SMILESCopy InChI

Affinity DataEC50:  81.8nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair

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In DepthDetails US Patent
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