Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Guanylate cyclase soluble subunit alpha-1/beta-1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM280864
(3-(4-{4-Amino-2-[6-chloro-1-(2-fluorobenzyl)-1H-in...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.227nM
Assay Description:
The binding buffer was composed of 50 mM triethanolamine, pH 7.4, 3 mM MgCl2, 0.025% BSA, 2 mM dithiothreitol (DTT), 300 μM DETA/NO and 400 _...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Guanylate cyclase soluble subunit alpha-1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM280864
(3-(4-{4-Amino-2-[6-chloro-1-(2-fluorobenzyl)-1H-in...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.227nM
pH: 7.4
Assay Description:
The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI