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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant MMP2 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant MMP9 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed