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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by
ChEMBL
Ligand
BDBM50148231
(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
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Affinity Data
IC50: 0.700nM
Assay Description:
Inhibition of human recombinant MMP2 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148231
(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
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Affinity Data
IC50: 0.900nM
Assay Description:
Inhibitory activity against matrix metalloprotease-13 (MMP-13)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)
Curated by
ChEMBL
Ligand
BDBM50148231
(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
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Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of human recombinant MMP9 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50148231
(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibitory activity against human matrix metalloprotease-1 (MMP-1)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI