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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Carbonic anhydrase 9
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
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Affinity Data
Ki: 3.30nM
Assay Description:
Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
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Affinity Data
Ki: 4.20nM
Assay Description:
Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 730nM
Assay Description:
Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
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Affinity Data
IC50: 0.120nM
Assay Description:
Inhibition of MMP13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.210nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.290nM
Assay Description:
Inhibition of MMP8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-16
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.310nM
Assay Description:
Inhibition of MMP16
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
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Affinity Data
IC50: 0.320nM
Assay Description:
Inhibition of MMP14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.350nM
Assay Description:
Inhibition of human recombinant MMP2 transfected in mouse melanoma cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
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Affinity Data
IC50: 7.80nM
Assay Description:
Inhibition of MMP1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Instituto Superior TéCnico
Curated by
ChEMBL
Ligand
BDBM50246599
(CHEMBL471537 | N-(4-Phenoxybenzenesulfonyl)-N-{[2-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 55nM
Assay Description:
Inhibition of TACE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI