Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50:  90nMAssay Description:Inhibition of aggrecanase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50:  1.64E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of aggrecanase2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258917((R)-2-(4'-((4-(cyclohexanecarbonyl)phenoxy)methyl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed