Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50356246(CHEMBL1910652)Copy SMILESCopy InChI

Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50356246(CHEMBL1910652)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI