Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50109042(CHEMBL181785)Copy SMILESCopy InChI

Affinity DataIC50:  2.40E+4nMAssay Description:Antagonist activity at cIAP1-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Astex Pharmaceuticals

Curated by ChEMBL

LigandBDBM50109042(CHEMBL181785)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+6nMAssay Description:Antagonist activity at XIAP-BIR3 domain (unknown origin) assessed as inhibition of interaction with SMAC by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLKEGGPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI