Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCaspase-1(Mus musculus)
Idun Pharmaceuticals

Curated by ChEMBL

LigandBDBM50072049(CHEMBL420619 | {(S)-1-[(S)-2-((S)-2-Hydroxy-5-oxo-...)Copy SMILESCopy InChI

Affinity DataIC50:  95nMAssay Description:Inhibitory activity against Caspase-1 using Ac-TyrValAlaAsp-amc as substrateMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCaspase-3(Homo sapiens (Human))
Idun Pharmaceuticals

Curated by ChEMBL

LigandBDBM50072049(CHEMBL420619 | {(S)-1-[(S)-2-((S)-2-Hydroxy-5-oxo-...)Copy SMILESCopy InChI

Affinity DataIC50:  3.49E+3nMAssay Description:Inhibitory activity against human Caspase-3 using Ac-AspGluValAsp as substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI