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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Caspase-9
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
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Affinity Data
IC50: 5nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Caspase-9 enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Caspase-8
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Caspase-8 enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-7
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Caspase-7 enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-6
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Caspase-6 enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-1
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Caspase-1 enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-3
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibitory activity against human recombinant Caspase-3 enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Caspase-3
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 30nM
Assay Description:
Inhibitory activity against human recombinant caspase-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Calpain-1 catalytic subunit
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Calpain 1 enzyme
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cathepsin B
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Compound was evaluated for its inhibitory activity against Cathepsin B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Replicase polyprotein 1ab
(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn
Ligand
BDBM429218
(jm5b01461, Compound 54)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
This is a review article.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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PC cid
PC sid
In Depth
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Article
PubMed
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Target
Prothrombin
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Maxim Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50140543
(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Compound was evaluated for its inhibitory activity against the Coagulation factor X
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI