Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020915(CHEMBL3287008 | US9216962, CFH412-S)
Affinity DataIC50:  58nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020915(CHEMBL3287008 | US9216962, CFH412-S)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant human HDAC3 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020915(CHEMBL3287008 | US9216962, CFH412-S)
Affinity DataIC50:  87nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Puyi Chemical

US Patent
LigandPNGBDBM50020915(CHEMBL3287008 | US9216962, CFH412-S)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant human HDAC1 using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening

Curated by ChEMBL
LigandPNGBDBM50020915(CHEMBL3287008 | US9216962, CFH412-S)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(epsilon-acetyl)-AMC as substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese National Center For Drug Screening

Curated by ChEMBL
LigandPNGBDBM50020915(CHEMBL3287008 | US9216962, CFH412-S)
Affinity DataIC50:  3.72E+3nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
In DepthDetails US Patent