Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCollagenase 3(Bos taurus)
Wyeth Research

Curated by ChEMBL

LigandBDBM50170301((S)-2-{4'-[(Benzofuran-2-ylmethyl)-amino]-biphenyl...)Copy SMILESCopy InChI

Affinity DataIC50:  4.90nMAssay Description:Inhibitory concentration against MMP-13 of bovine articular cartilage explantsMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target72 kDa type IV collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50170301((S)-2-{4'-[(Benzofuran-2-ylmethyl)-amino]-biphenyl...)Copy SMILESCopy InChI

Affinity DataIC50:  23nMAssay Description:Inhibitory concentration against MMP-2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL

LigandBDBM50170301((S)-2-{4'-[(Benzofuran-2-ylmethyl)-amino]-biphenyl...)Copy SMILESCopy InChI

Affinity DataIC50:  6.60E+3nMAssay Description:Inhibitory concentration against MMP-14More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI