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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetStromelysin-1(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084292(2-(3'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084292(2-(3'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084292(2-(3'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084292(2-(3'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50:  8.60E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084292(2-(3'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084292(2-(3'-Fluoro-biphenyl-4-sulfonylamino)-3-methyl-bu...)
Affinity DataIC50:  6.50E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed