Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetStromelysin-1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  5.40E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  2.57E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  2.60E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  7.10E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24032((2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The recombinant Agg-1 proteins pretreated with the various concentrations of the compound for 10 to 15 min. The reaction was initiated by addition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed