Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  600nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28487((2S)-3-methyl-2-{8-oxatricyclo[7.4.0.0^{2,7}]tride...)
Affinity DataIC50:  2.50E+4nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed