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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  19nMAssay Description:Inhibition of MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  52nMAssay Description:Inhibition of MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant MMP8 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  240nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of MMP1 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361600(CHEMBL1939845)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of TACE using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed