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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM30141
(alpha-sulfone piperidine hydroxamate, 11d)
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Affinity Data
IC50: 2nM
pH: 7.4 T: 2°C
Assay Description:
Compounds were tested for their ability to inhibit the cleavage of the substrate by the purified enzyme in a fluorescence-based fluorescence resonanc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM30141
(alpha-sulfone piperidine hydroxamate, 11d)
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Affinity Data
IC50: 415nM
T: 2°C
Assay Description:
A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Wyeth Research
Ligand
BDBM30141
(alpha-sulfone piperidine hydroxamate, 11d)
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Copy InChI
Affinity Data
IC50: 1.24E+3nM
T: 2°C
Assay Description:
A continuous assay was used in which the substrate is a synthetic peptide containing a fluorescent group (7-methoxycoumarin), which is quenched by en...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI