Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035237(2-(2-Hydroxycarbamoylmethyl-3-methyl-butyrylamino)...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against Leu-enkeph of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035237(2-(2-Hydroxycarbamoylmethyl-3-methyl-butyrylamino)...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035237(2-(2-Hydroxycarbamoylmethyl-3-methyl-butyrylamino)...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against human bronchiolar smooth muscle Endothelin-converting enzyme 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035237(2-(2-Hydroxycarbamoylmethyl-3-methyl-butyrylamino)...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against big ET-1 of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50035237(2-(2-Hydroxycarbamoylmethyl-3-methyl-butyrylamino)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against thermolysin with 0.5 uM [Leu5]-enkephalin (NEN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed