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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064120((S)-2-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonomet...)
Affinity DataIC50:  51nMAssay Description:Inhibitory activity was assessed on CHO cells expressing recombinant human Endothelin-converting enzyme 1 (ECE-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064120((S)-2-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonomet...)
Affinity DataIC50:  51nMAssay Description:In Vitro inhibition of recombinant human endothelin converting enzyme-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50064120((S)-2-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonomet...)
Affinity DataIC50:  6.70E+3nMAssay Description:In vitro inhibition of rat neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50064120((S)-2-[(S)-5-(2,4-Difluoro-phenyl)-2-(phosphonomet...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed