Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Amgen

LigandBDBM93420(PHD Inhibitor, 12{3,1,4})Copy SMILESCopy InChI

Affinity DataIC50:  32nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Amgen

LigandBDBM93420(PHD Inhibitor, 12{3,1,4})Copy SMILESCopy InChI

Affinity DataIC50:  77nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

LigandBDBM93420(PHD Inhibitor, 12{3,1,4})Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+3nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI