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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Matrilysin
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: 56nM
Assay Description:
Inhibition of human recombinant MMP-7 (Leu18 to Lys267 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: 1.70E+4nM
Assay Description:
Inhibition of human recombinant C-terminal 10-His tagged MMP-14 ( Ala21 to Gly284 residues) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
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PC sid
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PubMed
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: 2.80E+4nM
Assay Description:
Inhibition of human recombinant MMP-12 (Leu17 to Cys470 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
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PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: 4.50E+4nM
Assay Description:
Inhibition of human recombinant MMP-2 ( Ile34 to Cys660 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant MMP-13 (Leu20 to Cys471 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincub...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant MMP-9 (Ala20 to Asp707 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant MMP-3 (Tyr18 to Cys477 residues ) using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as fluorogenic substra...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Interstitial collagenase
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant MMP-1 (Phe20 to Asn469 residue) using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preinc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50589866
(CHEMBL5192674)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of human recombinant MMP-8 (Phe21 to Gly467 residues) using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as fluorogenic substrate preincuba...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
Copy BDB DOI