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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50074659
((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
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Affinity Data
IC50: 0.600nM
Assay Description:
Inhibition of integrin alpha4-beta1 binding to VCAM-Ig
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50074659
((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of integrin alpha4-beta1 adhesion to Jurkat cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Integrin alpha-4/beta-7
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50074659
((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
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Affinity Data
IC50: 8.00E+3nM
Assay Description:
Inhibition of integrin alpha4-beta7 adhesion to JY cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Integrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50074659
((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of ICAM-1 transfected CHO cell adhesion to integrin alphaL-beta2 of human JY cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Integrin alpha-5/beta-1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50074659
((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of integrin alpha5-beta1 adhesion to K562 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50074659
((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of integrin alpha1-beta1 adhesion using K562 cells expressing alpha-1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-IIb/beta-3
(Homo sapiens (Human))
Biogen
Curated by
ChEMBL
Ligand
BDBM50074659
((S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[4-(3-o-...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of integrin alphaIIb-beta3 adhesion to human citreated platelets
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI