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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Heme oxygenase 1
(Rattus norvegicus (rat))
University Of Catania
Curated by
ChEMBL
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
IC50: 410nM
Assay Description:
Inhibition of rat spleen microsome HO-1 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chromatography
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
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KEGG
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PC sid
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In Depth
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Article
PubMed
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Target
Lanosterol 14-alpha demethylase
(Homo sapiens (Human))
Act
Curated by
ChEMBL
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
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KEGG
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PC sid
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In Depth
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Article
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Target
Heme oxygenase 2
(Rattus norvegicus (rat))
University Of Catania
Curated by
ChEMBL
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
IC50: 5.00E+3nM
Assay Description:
Inhibition of rat brain microsome HO-2 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chromatography
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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DrugBank
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Nuclear receptor subfamily 1 group I member 2
(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center
Curated by
ChEMBL
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
EC50: 8.90E+3nM
Assay Description:
Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysis
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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DrugBank
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Nuclear receptor subfamily 1 group I member 2
(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center
Curated by
ChEMBL
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
EC50: 1.41E+4nM
Assay Description:
Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysis
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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Purchase
DrugBank
KEGG
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Orf1a protein
(MERS-CoV)
University of Bonn
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
EC50: 1.22E+4nM
Assay Description:
This is a review article.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
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GoogleScholar
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PC sid
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In Depth
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Article
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Target
Replicase polyprotein 1ab
(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University of Bonn
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
EC50: 1.53E+4nM
Assay Description:
This is a review article.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
DrugBank
KEGG
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Nuclear receptor subfamily 1 group I member 2
(Rattus norvegicus)
National Institutes Of Health Chemical Genomics Center
Curated by
ChEMBL
Ligand
BDBM50375318
(Fungistat | Gyno-Terazol | Panlomyc | R-42470 | TE...)
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Affinity Data
EC50: 9.10E+3nM
Assay Description:
Activation of rat PXR expressed in human HepG2 cells after 24 hrs by luciferase reporter gene based luminescent analysis
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI