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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
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Affinity Data
Ki: 0.400nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4nM
Assay Description:
Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
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Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 66.8nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Norepinephrine transporter
(RAT)
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 285nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.430nM
Assay Description:
Inhibition of [3H]WIN-35428l binding to Dopamine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.430nM
Assay Description:
Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
National Institute On Drug Abuse
Curated by
ChEMBL
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 285nM
Assay Description:
Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Virginia Commonwealth University
Curated by
PDSP K
i
Database
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 310nM
Assay Description:
Inhibition of [3H]paroxetine binding to Serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transporter
(Rattus norvegicus)
National Institute On Drug Abuse
Curated by
ChEMBL
Ligand
BDBM50006784
(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 864nM
Assay Description:
Inhibition of [3H]mazindol binding to Norepinephrine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI