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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
57
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Target
Fatty acid-binding protein, liver
(Homo sapiens (Human))
Texas A&M University
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Ki: 15nM
Assay Description:
A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...
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Target
Fatty acid-binding protein, liver [T94A]
(Homo sapiens (Human))
Texas A&M University
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Ki: 15nM
Assay Description:
A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Ki: 24nM
Assay Description:
Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP high binding affinity site expressed in Escherichia coli BL21 by co...
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Ki: 100nM
Assay Description:
A solution of the L-FABP (500 nM) and ANS (35 µM) was titrated with phytanic acid (0-6.4 µM) or fenofibrate (0-6 µM for the rat L-FABP...
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Ki: 405nM
Assay Description:
Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP low binding affinity site expressed in Escherichia coli BL21 by com...
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Target
Fatty acid-binding protein, intestinal
(Homo sapiens (Human))
Monash University
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Ki: 6.10E+3nM ΔG°: -56.5kJ/mole
T: 2°C
Assay Description:
Briefly, steady-state fluorescence spectra of ANS binding was monitored by measuring the increase in fluorescence signal between 450?550 nm following...
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Target
Solute carrier organic anion transporter family member
(Danio rerio (Zebrafish))
Rudjer Boskovic Institute
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Ki: 5.44E+4nM
Assay Description:
In the inhibition experiments, the cells were preincubated for 20 s with test compounds, followed by a 5-min incubation with [3H]E3S (5 nM) or 30-min...
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of human PPARalpha receptor by scintillation proximity assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of human PPARgamma receptor by scintillation proximity assay
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Target
Broad substrate specificity ATP-binding cassette transporter ABCG2
(Homo sapiens (Human))
Federal University Of Parana
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: 5.10E+3nM
Assay Description:
Inhibition of ABCG2 (unknown origin) expressed in human HEK293-A cells membrane vesicles assessed inhibition of ABCG2-mediated urate transport activi...
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: 1.53E+4nM
Assay Description:
Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: 1.53E+4nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: 4.10E+4nM
Assay Description:
Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...
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Target
Cruzipain
(Trypanosoma cruzi)
University Of California San Francisco
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: 6.10E+4nM
Assay Description:
Inhibition of Trypanosoma cruzi cruzaine preincubated for 5 mins before substrate addition by fluorescence assay in absence of Triton X-100
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Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
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Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
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Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
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Target
Cruzipain
(Trypanosoma cruzi)
University Of California San Francisco
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
IC50: >5.00E+5nM
Assay Description:
Inhibition of Trypanosoma cruzi cruzaine preincubated for 5 mins before substrate addition by fluorescence assay in presence of 0.01% Triton X-100
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+5nM
Assay Description:
Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assay
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Target
Peroxisome proliferator-activated receptor alpha
(Mus musculus)
Glaxo Wellcome Research & Development
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 1.80E+4nM
Assay Description:
Agonist activity for murine PPAR alpha receptor in transcriptional activation assay
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 2.00E+3nM
Assay Description:
Agonist activity at human PPARalpha receptor expressed in african green monkey COS1 cells cotransfected with fused yeast Gal4-DBD by transactivation ...
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 18nM
Assay Description:
Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 5 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 130nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 5 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 23nM
Assay Description:
Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 10 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 150nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 10 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 24nM
Assay Description:
Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 15 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 160nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 15 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 27nM
Assay Description:
Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 20 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 200nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 20 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 32nM
Assay Description:
Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 25 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 250nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 25 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 41nM
Assay Description:
Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 30 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 270nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 30 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 62nM
Assay Description:
Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 37 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 320nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 37 deg C by fluorimetric assay
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Target
Fatty acid-binding protein, liver
(Rattus norvegicus (Rat))
Monash University (Parkville Campus)
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 360nM
Assay Description:
Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 42 deg C by fluorimetric assay
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.35E+4nM
Assay Description:
Agonist activity at human PPARalpha assessed as luciferase activity by transactivation assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 4.10E+4nM
Assay Description:
Binding affinity at PPARgamma
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Target
Peroxisome proliferator-activated receptor alpha
(Rattus norvegicus)
Johnson & Johnson
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at rat PPARalpha in rat H4IIE cells assessed as gene induction
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.35E+4nM
Assay Description:
Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+5nM
Assay Description:
Agonist activity for Human PPAR gamma receptor in transcriptional activation assay
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Target
Fatty acid-binding protein, intestinal
(Homo sapiens (Human))
Monash University
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
Kd: 4.41E+3nM
pH: 8.0 T: 2°C
Assay Description:
ITC experiments were carried out using an iTC200 microcalorimeter (MicroCal) with coin shaped sample cell (200 μL) at 37 C with stirring at 1000...
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 2.00E+4nM
Assay Description:
Agonist activity at PPARalpha
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+4nM
Assay Description:
Agonist activity at GAL4-fused PPARalpha LBD (unknown origin) expressed in HEK293 cells assessed as receptor transactivation after 18 hrs by dual luc...
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 5.00E+4nM
Assay Description:
Transactivation of human GAL4-fused PPARalpha LBD expressed in human HepG2 cells after 24 hrs by renilla luciferase reporter gene assay
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+4nM
Assay Description:
Agonist activity at PPARalpha (unknown origin)
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+5nM
Assay Description:
Agonist activity at PPARgamma (unknown origin)
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+4nM
Assay Description:
Agonist activity at PPARalpha (unknown origin)
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+4nM
Assay Description:
Effective concentration against human peroxisome proliferator activated receptor alpha in Gal4 transactivation assay
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 5.00E+4nM
Assay Description:
In vitro effective concentration for agonist activity on dog Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected C...
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 4.10E+4nM
Assay Description:
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...
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Target
Peroxisome proliferator-activated receptor alpha
(Rattus norvegicus)
Johnson & Johnson
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 4.90E+4nM
Assay Description:
In vitro effective concentration for agonist activity on rat Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected C...
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 570nM
Assay Description:
In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.21E+3nM
Assay Description:
In vitro activation of human peroxisome proliferator activated receptor alpha
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Target
Peroxisome proliferator-activated receptor gamma
(Mus musculus)
Glaxo Wellcome Research & Development
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 2.50E+5nM
Assay Description:
Agonist activity for murine PPAR gamma receptor in transcriptional activation assay
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: 3.00E+4nM
Assay Description:
Agonist activity for Human PPAR alpha receptor in transcriptional activation assay
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Target
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50085042
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
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Affinity Data
EC50: >5.00E+3nM
Assay Description:
Agonist activity at human PPARgamma receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...
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