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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
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Target
Macrophage metalloelastase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 410nM
Assay Description:
Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Collagenase 3
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 7.90E+3nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-16
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 1.80E+4nM
Assay Description:
Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 2.40E+4nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Stromelysin-1
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: 5.40E+4nM
Assay Description:
Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Interstitial collagenase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50299057
((R)-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-met...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI