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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetFKBP12A/mTOR(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50:  125nMAssay Description:Inhibition of human full length recombinant mTOR/FKBP12 in presence of [gamma-33P]ATP incubated for 40 mins by radiometric scintillation counting ana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50:  136nMAssay Description:Inhibition of human full length recombinant mTOR in presence of [gamma-33P]ATP incubated for 40 mins by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50:  2.15E+3nMAssay Description:Inhibition of recombinant human full length PI3K p110delta/p85a using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50:  2.72E+3nMAssay Description:Inhibition of human PI3K-C2alpha (299 to ens residues) using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50:  9.44E+3nMAssay Description:Inhibition of human recombinant B-Raf (416 to end residues) using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed