Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetInterleukin-1 receptor-associated kinase 3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50560892(CHEMBL4752190)Copy SMILESCopy InChI

Affinity DataIC50:  33nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair

Target InfoPDBNCI pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoKEGGPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50560892(CHEMBL4752190)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human full-length His-tagged IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoKEGGPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI