Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  2.90nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

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TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human CDK9/cyclin T expressed in insect cells using CDK7/9-tide as substrate after 30 mins in presence of [gamma-33P] by sc...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human CDK5/p25 after 30 mins in presence of [gamma-33P] by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  68nMAssay Description:Inhibition of recombinant human CDK2/cyclin A after 30 mins in presence of [gamma-33P] by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetDual specificity protein kinase CLK4(Mus musculus)
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  89nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  89nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetDual specificity protein kinase CLK1(Mus musculus)
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Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  100nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant GST-tagged human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant GST-tagged human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant GST-tagged human DYRK2 expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] b...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetDual specificity protein kinase CLK2(Homo sapiens (Human))TBA

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  130nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
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TargetDual specificity protein kinase CLK2(Mus musculus)
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  320nMAssay Description:Inhibition of porcine brain GSK3 using GS-1 as substrate after 30 mins in presence of [gamma-33P] by scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant GST-tagged human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins in presence of [gamma-33P] b...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity protein kinase CLK3(Mus musculus)
Universit£

Curated by ChEMBL

LigandBDBM50469189(CHEMBL4284209)Copy SMILESCopy InChI

Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins in presence of [gamma-33P] ...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI