Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Pharmakea

US Patent

LigandBDBM555714(US11345676, Compound 1-306 | US11345676, Example 1...)Copy SMILESCopy InChI

Affinity DataIC50: <300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo™ Kinase Assay and Myelin Basic Pr...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea

US Patent

LigandBDBM555714(US11345676, Compound 1-306 | US11345676, Example 1...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+3nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI