Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50034495(CHEMBL3359262)Copy SMILESCopy InChI

Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50034495(CHEMBL3359262)Copy SMILESCopy InChI

Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50034495(CHEMBL3359262)Copy SMILESCopy InChI

Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human ERG channel by patch-clamp assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI