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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
University Of Wisconsin School Of Medicine And Public Health
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.00500nM
Assay Description:
Displacement of (+)-[3H]pentazocine from sigma 1 receptor in guinea pig brain microsomes
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
University Of Wisconsin School Of Medicine And Public Health
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.00500nM
Assay Description:
Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in guinea pig whole brain microsomes
More data for this Ligand-Target Pair
Target Info
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
University Of Wisconsin School Of Medicine And Public Health
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.00500nM
Assay Description:
Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig
More data for this Ligand-Target Pair
Target Info
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.0100nM
Assay Description:
Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
University Of Wisconsin School Of Medicine And Public Health
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.0110nM
Assay Description:
Displacement of (+)-[3H]pentazocine from sigma 1 receptor in guinea pig liver microsomes
More data for this Ligand-Target Pair
Target Info
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Target
Sigma non-opioid intracellular receptor 1
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.0110nM
Assay Description:
Displacement of [3H]-pentazocine from sigma 1 opioid receptor in rat liver homogenate by liquid scintillation counting
More data for this Ligand-Target Pair
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
University Of Wisconsin School Of Medicine And Public Health
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Copy InChI
Affinity Data
Ki: 0.0110nM
Assay Description:
Displacement of (+)-[3H]-pentazocine from sigma 1 receptor in guinea pig liver microsomes
More data for this Ligand-Target Pair
Target Info
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Target
C-8 sterol isomerase ERG2
(Saccharomyces cerevisiae)
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.0500nM
Assay Description:
Affinity for ERG2 of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine radioligand
More data for this Ligand-Target Pair
Target Info
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.0800nM
Assay Description:
Displacement of (+)-[3H]pentazocine from sigma 1 receptor expressed in Saccharomyces cerevisiae WA0
More data for this Ligand-Target Pair
Target Info
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Target
Sigma non-opioid intracellular receptor 1
(Cavia porcellus (Guinea pig))
University Of Wisconsin School Of Medicine And Public Health
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 0.0800nM
Assay Description:
Displacement of (+)-[3H]-pentazocine from recombinant guinea pig His6-tagged sigma 1 receptor expressed in Saccharomyces cerevisiae WAO microsomes
More data for this Ligand-Target Pair
Target Info
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Target
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 17nM
Assay Description:
Displacement of (+)-[3H]-pentazocine from recombinant human sigma 1 receptor expressed in baculovirus infected Sf9 insect cell membranes after 90 min...
More data for this Ligand-Target Pair
Target Info
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Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
(Homo sapiens (Human))
University Of Innsbruck
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 30nM
Assay Description:
Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand
More data for this Ligand-Target Pair
Target Info
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Target
Sigma intracellular receptor 2
(Rattus norvegicus (Rat))
Virginia Commonwealth University
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
Ki: 854nM
Assay Description:
Displacement of (+)-[3H]-ditolylguanidine from recombinant rat sigma 2 receptor expressed in rat PC12 cell membranes after 90 mins in presence of sig...
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Target
Cycloeucalenol cycloisomerase
(Zea mays)
Institut De Botanique
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
IC50: 400nM
Assay Description:
Inhibition of Zea mays (maize) cycloeucalenol-obtusifolial isomerase
More data for this Ligand-Target Pair
Target Info
MMDB
NCI pathway
Reactome pathway
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Target
Sterol-8,7-isomerase
(Zea mays)
Institut De Botanique
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
IC50: 400nM
Assay Description:
Inhibition of Zea mays (maize) delta8,delta7-sterol isomerase
More data for this Ligand-Target Pair
Target Info
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
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Target
Delta(14)-sterol reductase
(Zea mays)
Institut De Botanique
Curated by
ChEMBL
Ligand
BDBM50170654
((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...)
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Affinity Data
IC50: 800nM
Assay Description:
Inhibition of Zea mays (maize) microsomal delta 8,14-steroid 14-reductase using delta 8,14-cholestadienol as substrate after 90 min by GC analysis
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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